![]() ![]() There are no adequate and well-controlled studies in human pregnant women. Reduced ossification of the frontal and parietal bones of the skull was noted infrequently (<3%) in fetuses of rabbit dams immunized to rhBMP-2 however, there was no effect noted in limb bud development. ▪In an experimental rabbit study, rhBMP-2 has been shown to elicit antibodies that are capable of crossing the placenta. It should not be used in people with immune deficiencies due to other treatments, such as radiation therapy, chemotherapy, or steroid therapy.It should not be used in pregnant women, women who plan to become pregnant in the next 12 months, or women who are nursing.It cannot be used in patients with an active infection at the defect site.It has not been studied for use in patients under 18 years of age. ![]() There are some risks associated with Infuse Bone Graft: WHAT ARE THE DRAWBACKS OF USING INFUSE BONE GRAFT? Infuse Bone Graft eliminated pain and complications related to a secondary bone harvesting procedure.Infuse Bone Graft was found to be safe and effective.Rates of fusion, although not statistically significant, were 94.5% in the Infuse Bone Graft group and 88.7% in the autograft group at 24 months. ![]()
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